Loki doesn't resist the touch to his wrists or even seem alarmed, but he does look a little confused by it. Thor has always been quick to embrace him, and so was Frigga, so he does know when comfort is being offered, but to his mind he's just made a dreadful confession of his own guilt, not a plea for reassurance.

He blinks at Megatron, further surprised by the message he seems to have taken from this confession, and after a moment he reaches up and pats his cheek. "At first glance, you reminded me of him, but not because of anything you've done to me. Just the silhouette. Broad shoulders, strong jaw...it took me a moment to adjust, but I do not mistake you for Thanos now."

"And he's dead in my world anyway, and in many others. Though he got to me first, and--that's not relevant. What I meant was that I have a lot of innocent blood on my hands, as well. I didn't ask to participate in the Culls, but I didn't stop them either, and when I visited Earth, I did terrible things as much on my own behalf as the Order's. That was when I was a monster. But it is a matter of some reassurance that they had to break me first."

After a moment, he leans lightly into Megatron's shoulder, recognizing the offer of touch, if somewhat awkward accepting it.